| Primary information |
|---|
| ID | 33301 |
| Uniprot ID | O00220 |
| Description | Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | Palmitoylated (PubMed-19090789). Palmitoylation of TNFRSF10A is required for its association with lipid rafts; oligomerization and function in TRAIL-induced cell death (PubMed-19090789). Palmitoylated by ZDHHC3 (Probable). |
| Function | Receptor for the cytotoxic ligand TNFSF10/TRAIL |
| Length | 468 |
| Molecular Weight | 50089 |
| Reference | 9082980; 14702039; 1 |
| Hormone | NA |
| PDB ID | NA
|