Detailed description page of Hmrbase2

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33288 details
Primary information
ID33288
Uniprot IDQ9Y6N7
DescriptionRoundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationUbiquitinated. May be deubiquitinated by USP33.
FunctionReceptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration; including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development
Length1651
Molecular Weight180930
Reference9458045; 16641997; 1
HormoneNA
PDB IDNA