| Primary information |
|---|
| ID | 33286 |
| Uniprot ID | Q14242 |
| Description | P-selectin glycoprotein ligand 1 (PSGL-1) (Selectin P ligand) (CD antigen CD162) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | Displays complex; core-2; sialylated and fucosylated O-linked oligosaccharides; at least some of which appear to contain poly-N-acetyllactosamine with varying degrees of substitution. Mainly disialylated or neutral forms of the core-2 tetrasaccharide; Galbeta1--4GlcNAcbeta1--6(Galbeta1--3)GalNAcOH. The GlcN-GalN ratio is approximately 2-1 and the Man-Fuc ratio 3-5. Contains about 14% fucose with alpha-1;3 linkage present in two forms- One species is a disialylated; monofucosylated glycan; and th |
| Function | A SLe(x)-type proteoglycan; which through high affinity; calcium-dependent interactions with E-; P- and L-selectins; mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture. |
| Length | 412 |
| Molecular Weight | 43201 |
| Reference | 7541799; 7505206; 14 |
| Hormone | NA |
| PDB ID | NA
|