| Primary information |
|---|
| ID | 33277 |
| Uniprot ID | Q9UIW2 |
| Description | Plexin-A1 (Semaphorin receptor NOV) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | Coreceptor for SEMA3A; SEMA3C; SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance; invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins; and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. |
| Length | 1896 |
| Molecular Weight | 211067 |
| Reference | 16641997; 8570614; 1 |
| Hormone | NA |
| PDB ID | NA
|