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33253 details
Primary information
ID33253
Uniprot IDQ9GZZ7
DescriptionGDNF family receptor alpha-4 (GDNF receptor alpha-4) (GDNFR-alpha-4) (GFR-alpha-4) (Persephin receptor)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular Location[Isoform GFRalpha4a]- Cell membrane; Lipid-anchor; GPI-anchor.; [Isoform GFRalpha4b]- Cell membrane;
Developmental StageNA
SimilarityNA
Post Translational ModificationNA
FunctionReceptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and; in the postnatal development of the adrenal medulla.
Length299
Molecular Weight31670
Reference11116144; 11780052;
HormoneNA
PDB IDNA