| Primary information |
|---|
| ID | 33244 |
| Uniprot ID | P16070 |
| Description | CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | Expressed in the developing retina between 16 and 19 weeks post-conception; specifically in the outer neuroblastic zone; inner neuroblastic zone; interphotoreceptor zone and the retinal pigment epithelium (at protein level). |
| Similarity | NA |
| Post Translational Modification | Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors. |
| Function | Cell-surface receptor that plays a role in cell-cell interactions; cell adhesion and migration; helping them to sense and respond to changes in the tissue microenvironment |
| Length | 742 |
| Molecular Weight | 81538 |
| Reference | 2466575; 1840487; 19 |
| Hormone | NA |
| PDB ID | NA
|