Detailed description page of Hmrbase2

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33230 details
Primary information
ID33230
Uniprot IDQ9Y5X5
DescriptionNeuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane; Multi-pass membrane protein.
Developmental StageNA
SimilarityNA
Post Translational ModificationNA
FunctionReceptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides; also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Length522
Molecular Weight60270
Reference10079187; 10851242;
HormoneNA
PDB IDNA