| Primary information |
|---|
| ID | 33210 |
| Uniprot ID | Q92859 |
| Description | Neogenin (Immunoglobulin superfamily DCC subclass member 2) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes; including neural tube and mammary gland formation; myogenesis and angiogenesis. Receptor for members of the BMP; netrin; and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion; the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. |
| Length | 1461 |
| Molecular Weight | 160017 |
| Reference | 9121761; 9169140; 16 |
| Hormone | NA |
| PDB ID | NA
|