Detailed description page of Hmrbase2

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33192 details
Primary information
ID33192
Uniprot IDP16871
DescriptionInterleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CDw127) (CD antigen CD127)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular Location[Isoform 1]- Cell membrane; Single-pass type I membrane protein.; [Isoform 3]- Cell membrane; Single
Developmental StageNA
SimilarityNA
Post Translational ModificationN-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form.
FunctionReceptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Length459
Molecular Weight51579
Reference2317865; 2038316; 98
HormoneNA
PDB IDNA