| Primary information |
|---|
| ID | 33188 |
| Uniprot ID | Q01638 |
| Description | Interleukin-1 receptor-like 1 (EC 3.2.2.6) (Protein ST2) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | [Isoform C]- Cell membrane.; [Isoform B]- Secreted.; Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP. Its stimulation recruits MYD88; IRAK1; IRAK4; and TRAF6; followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2; MAPK14; and MAPK8. Possibly involved in helper T-cell function. |
| Length | 556 |
| Molecular Weight | 63358 |
| Reference | 1482686; 10527832; 1 |
| Hormone | NA |
| PDB ID | NA
|