| Primary information |
|---|
| ID | 33167 |
| Uniprot ID | Q13651 |
| Description | Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha) (IL-10R subunit alpha) (IL-10RA) (CDw210a) (Interleukin-10 receptor subunit 1) (IL-10R subunit 1) (IL-10R1) (CD antigen CD210) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | Phosphorylated. Phosphorylation of the cytoplasmic tail induced STAT3 activation. |
| Function | Cell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions; limiting excessive tissue disruption caused by inflammation. Upon binding to IL10; induces a conformational change in IL10RB; allowing IL10RB to bind IL10 as well |
| Length | 578 |
| Molecular Weight | 63003 |
| Reference | 8120391; 14702039; 1 |
| Hormone | NA |
| PDB ID | NA
|