Detailed description page of Hmrbase2

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33162 details
Primary information
ID33162
Uniprot IDP11717
DescriptionCation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth fact
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationGolgi apparatus membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationPalmitoylated (PubMed-18817523). Undergoes cysteine S-palmitoylation which promotes interaction with the retromer cargo-selective complex which mediates its retrograde trafficking to the Golgi apparatus (PubMed-18817523).
FunctionMediates the transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes
Length2491
Molecular Weight274375
Reference2957598; 2963003; 98
HormoneNA
PDB IDNA