| Primary information |
|---|
| ID | 33154 |
| Uniprot ID | Q9NP59 |
| Description | Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | Polyubiquitinated by RNF217; leading to proteasomal degradation. Ubiquitination is necessary for its internalization by hepcidin/HAMP (PubMed-22682227). |
| Function | Major iron transporter that plays a key role in balancing cellular and systemic iron levels |
| Length | 571 |
| Molecular Weight | 62542 |
| Reference | 10747949; 10882071; |
| Hormone | NA |
| PDB ID | NA
|