| Primary information |
|---|
| ID | 33153 |
| Uniprot ID | P25103 |
| Description | Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is- substance P substance K neuromedin-K. |
| Length | 407 |
| Molecular Weight | 46251 |
| Reference | 1718267; 1659396; 16 |
| Hormone | NA |
| PDB ID | NA
|