Detailed description page of Hmrbase2

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33143 details
Primary information
ID33143
Uniprot IDP32927
DescriptionCytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationMembrane; Single-pass type I membrane protein.
Developmental StageNA
SimilarityNA
Post Translational ModificationMay be phosphorylated by LYN.
FunctionCell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA; IL5RA or CSF2RA
Length897
Molecular Weight97336
Reference1702217; 15461802; 1
HormoneNA
PDB IDNA