Detailed description page of Hmrbase2

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33139 details
Primary information
ID33139
Uniprot IDP48546
DescriptionGastric inhibitory polypeptide receptor (GIP-R) (Glucose-dependent insulinotropic polypeptide receptor)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane; Multi-pass membrane protein.
Developmental StageNA
SimilarityNA
Post Translational ModificationN-glycosylation is required for cell surface expression and lengthens receptor half-life by preventing degradation in the ER.
FunctionThis is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Length466
Molecular Weight53157
Reference7589426; 7556958; 85
HormoneNA
PDB IDNA