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33134 details
Primary information
ID33134
Uniprot IDQ99062
DescriptionGranulocyte colony-stimulating factor receptor (G-CSF receptor) (G-CSF-R) (CD antigen CD114)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular Location[Isoform 2]- Secreted
Developmental StageNA
SimilarityNA
Post Translational ModificationN-glycosylated.
FunctionReceptor for granulocyte colony-stimulating factor (CSF3); essential for granulocytic maturation. Plays a crucial role in the proliferation; differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
Length836
Molecular Weight92156
Reference2147944; 1701053; 15
HormoneNA
PDB IDNA