Detailed description page of Hmrbase2

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33122 details
Primary information
ID33122
Uniprot IDQ8WXI7
DescriptionMucin-16 (MUC-16) (Ovarian cancer-related tumor marker CA125) (CA-125) (Ovarian carcinoma antigen CA125)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane; Single-pass type I membrane protein. Secreted; extracellular space. Note=May be liber
Developmental StageNA
SimilarityNA
Post Translational ModificationHeavily O-glycosylated; expresses both type 1 and type 2 core glycans.
FunctionThought to provide a protective; lubricating barrier against particles and infectious agents at mucosal surfaces.
Length14507
Molecular Weight1519175
Reference15057824; 12218296;
HormoneNA
PDB IDNA