Detailed description page of Hmrbase2

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33121 details
Primary information
ID33121
Uniprot IDQ16581
DescriptionC3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane; Multi-pass membrane protein.
Developmental StageNA
SimilarityNA
Post Translational ModificationAmong the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.
FunctionReceptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis; granule enzyme release and superoxide anion production.
Length482
Molecular Weight53864
Reference8605247; 8765043; 87
HormoneNA
PDB IDNA