Detailed description page of Hmrbase2

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33100 details
Primary information
ID33100
Uniprot IDP24530
DescriptionEndothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationPalmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405.
FunctionNon-specific receptor for endothelin 1; 2; and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Length442
Molecular Weight49644
Reference1710450; 1648908; 17
HormoneNA
PDB IDNA