| Primary information |
|---|
| ID | 33089 |
| Uniprot ID | P49682 |
| Description | C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (CKR-L2) (G protein-coupled receptor 9) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | [Isoform 1]- Cell membrane |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding and subsequent signal transduction induction. |
| Function | [Isoform 1]- Receptor for the C-X-C chemokine CXCL9; CXCL10 and CXCL11 and mediates the proliferation; survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway |
| Length | 368 |
| Molecular Weight | 40660 |
| Reference | 9064356; 12782716; 1 |
| Hormone | NA |
| PDB ID | NA
|