Primary information |
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ID | 33082 |
Uniprot ID | P31391 |
Description | Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) (SST4) |
Organism | Homo sapiens |
Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | NA |
Function | Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase; but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells. |
Length | 388 |
Molecular Weight | 42003 |
Reference | 8512564; 8483934; 83 |
Hormone | NA |
PDB ID | NA
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