Primary information |
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ID | 33076 |
Uniprot ID | P42702 |
Description | Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118) |
Organism | Homo sapiens |
Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | [Isoform 1]- Cell membrane; Single-pass type I membrane protein.; [Isoform 2]- Secreted. |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | NA |
Function | Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells. |
Length | 1097 |
Molecular Weight | 123743 |
Reference | 1915266; 9525740; 18 |
Hormone | NA |
PDB ID | NA
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