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33076 details
Primary information
ID33076
Uniprot IDP42702
DescriptionLeukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular Location[Isoform 1]- Cell membrane; Single-pass type I membrane protein.; [Isoform 2]- Secreted.
Developmental StageNA
SimilarityNA
Post Translational ModificationNA
FunctionSignal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
Length1097
Molecular Weight123743
Reference1915266; 9525740; 18
HormoneNA
PDB IDNA