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33071 details
Primary information
ID33071
Uniprot IDP21854
DescriptionB-cell differentiation antigen CD72 (Lyb-2) (CD antigen CD72)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationMembrane; Single-pass type II membrane protein.
Developmental StageNA
SimilarityNA
Post Translational ModificationPhosphorylated upon engagement of the B-cell receptor; probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1.
FunctionPlays a role in B-cell proliferation and differentiation.
Length359
Molecular Weight40220
Reference2141045; 15489334
HormoneNA
PDB IDNA