Primary information |
---|
ID | 33055 |
Uniprot ID | P08138 |
Description | Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD) (CD antigen CD271) |
Organism | Homo sapiens |
Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Cell membrane |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | N- and O-glycosylated.; O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.; Phosphorylated on serine residues. |
Function | Low affinity receptor which can bind to NGF; BDNF; NTF3; and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF; BDNF and NTF3 with high affinity; and has much lower affinity for mature NGF and BDNF |
Length | 427 |
Molecular Weight | 45183 |
Reference | 3022937; 14702039; 1 |
Hormone | NA |
PDB ID | NA
|