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33055 details
Primary information
ID33055
Uniprot IDP08138
DescriptionTumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD) (CD antigen CD271)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationN- and O-glycosylated.; O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.; Phosphorylated on serine residues.
FunctionLow affinity receptor which can bind to NGF; BDNF; NTF3; and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF; BDNF and NTF3 with high affinity; and has much lower affinity for mature NGF and BDNF
Length427
Molecular Weight45183
Reference3022937; 14702039; 1
HormoneNA
PDB IDNA