Primary information |
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ID | 33041 |
Uniprot ID | O60603 |
Description | Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282) |
Organism | Homo sapiens |
Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Membrane |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | Glycosylation of Asn-442 is critical for secretion of the N-terminal ectodomain of TLR2. |
Function | Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides |
Length | 784 |
Molecular Weight | 89838 |
Reference | 9596645; 9435236; 97 |
Hormone | NA |
PDB ID | NA
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