Detailed description page of Hmrbase2

This page displays user query in tabular form.

33041 details
Primary information
ID33041
Uniprot IDO60603
DescriptionToll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationMembrane
Developmental StageNA
SimilarityNA
Post Translational ModificationGlycosylation of Asn-442 is critical for secretion of the N-terminal ectodomain of TLR2.
FunctionCooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides
Length784
Molecular Weight89838
Reference9596645; 9435236; 97
HormoneNA
PDB IDNA