Primary information |
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ID | 33032 |
Uniprot ID | O14836 |
Description | Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD antigen CD267) |
Organism | Homo sapiens |
Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Membrane; Single-pass type III membrane protein. |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | NA |
Function | Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT; as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. |
Length | 293 |
Molecular Weight | 31816 |
Reference | 9311921; 14702039; 1 |
Hormone | NA |
PDB ID | NA
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