Detailed description page of Hmrbase2

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33030 details
Primary information
ID33030
Uniprot IDP01130
DescriptionLow-density lipoprotein receptor (LDL receptor)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationN- and O-glycosylated.
FunctionBinds LDL; the major cholesterol-carrying lipoprotein of plasma; and transports it into cells by endocytosis. In order to be internalized; the receptor-ligand complexes must first cluster into clathrin-coated pits.
Length860
Molecular Weight95376
Reference6091915; 2988123; 14
HormoneNA
PDB IDNA