Primary information |
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ID | 33030 |
Uniprot ID | P01130 |
Description | Low-density lipoprotein receptor (LDL receptor) |
Organism | Homo sapiens |
Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Cell membrane |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | N- and O-glycosylated. |
Function | Binds LDL; the major cholesterol-carrying lipoprotein of plasma; and transports it into cells by endocytosis. In order to be internalized; the receptor-ligand complexes must first cluster into clathrin-coated pits. |
Length | 860 |
Molecular Weight | 95376 |
Reference | 6091915; 2988123; 14 |
Hormone | NA |
PDB ID | NA
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