Primary information |
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ID | 33028 |
Uniprot ID | O60494 |
Description | Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) |
Organism | Homo sapiens |
Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
Subcellular Location | Apical cell membrane |
Developmental Stage | NA |
Similarity | NA |
Post Translational Modification | The precursor is cleaved by a trans-Golgi proteinase furin; removing a propeptide. |
Function | Endocytic receptor which plays a role in lipoprotein; vitamin and iron metabolism by facilitating their uptake |
Length | 3623 |
Molecular Weight | 398736 |
Reference | 9572993; 15164054; 1 |
Hormone | NA |
PDB ID | NA
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