Detailed description page of Hmrbase2

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33019 details
Primary information
ID33019
Uniprot IDP31431
DescriptionSyndecan-4 (SYND4) (Amphiglycan) (Ryudocan core protein)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular Location[Isoform 1]- Membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationShedding is enhanced by a number of factors such as heparanase; thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
FunctionCell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP
Length198
Molecular Weight21642
Reference1500433; 7916598; 87
HormoneNA
PDB IDNA