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33016 details
Primary information
ID33016
Uniprot IDP21926
DescriptionCD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
OrganismHomo sapiens
TxonomyHomo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms
Subcellular LocationCell membrane
Developmental StageNA
SimilarityNA
Post Translational ModificationPalmitoylated at a low; basal level in unstimulated platelets. The level of palmitoylation increases when platelets are activated by thrombin (in vitro). The protein exists in three forms with molecular masses between 22 and 27 kDa; and is known to carry covalently linked fatty acids (PubMed-11959120). Palmitoylation by ZDHHC2 regulates CD9 expression; association with other tetraspanin family proteins and function in cell adhesion (PubMed-18508921).
FunctionIntegral membrane protein associated with integrins; which regulates different processes; such as sperm-egg fusion; platelet activation and aggregation; and cell adhesion
Length228
Molecular Weight25416
Reference1840589; 2037603; 17
HormoneNA
PDB IDNA