| Primary information |
|---|
| ID | 33002 |
| Uniprot ID | P27037 |
| Description | Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | On ligand binding; forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate; then bind and activate SMAD transcriptional regulators. Receptor for activin A; activin B and inhibin A |
| Length | 513 |
| Molecular Weight | 57848 |
| Reference | 1311955; 1314589; 14 |
| Hormone | NA |
| PDB ID | NA
|