| Primary information |
|---|
| ID | 32999 |
| Uniprot ID | P41968 |
| Description | Melanocortin receptor 3 (MC3-R) |
| Organism | Homo sapiens |
| Txonomy | Homo ; Homininae ; Hominidae ; Hominoidea ; Catarrhini ; Simiiformes ; Haplorrhini ; Primates ; Euarchontoglires ; Boreoeutheria ; Eutheria ; Theria ; Mammalia ; Amniota ; Tetrapoda ; Dipnotetrapodomorpha ; Sarcopterygii ; Euteleostomi ; Teleostomi ; Gnathostomata ; Vertebrata ; Craniata ; Chordata ; Deuterostomia ; Bilateria ; Eumetazoa ; Metazoa ; Opisthokonta ; Eukaryota ; cellular organisms |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Developmental Stage | NA |
| Similarity | NA |
| Post Translational Modification | NA |
| Function | Receptor for MSH (alpha; beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. |
| Length | 323 |
| Molecular Weight | 36043 |
| Reference | 8463333; 11780052; 1 |
| Hormone | NA |
| PDB ID | NA
|