Detailed description page of Hmrbase2

This page displays user query in tabular form.

32994 details
Primary information
ID32994
Uniprot IDQ6AXS4
DescriptionRenin receptor;Alternative Name- Renin/prorenin receptor;Alternative Name- ATPase; H(+)-transporting; lysosomal accessory protein 2;Alternative Name- ATPase; H(+)-transporting; lysosomal-interacting p
OrganismRattus norvegicus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular LocationMembrane; Single-pass type I membrane protein (Potential)
Developmental StageNA
SimilarityNA
Post Translational ModificationPhosphorylated.
FunctionFunctions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I; it may also play a role in the renin-angiotensin system (RAS).
Length350
Molecular Weight39082
ReferenceNA
HormoneP08424
PDB IDNA