Detailed description page of Hmrbase2

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32991 details
Primary information
ID32991
Uniprot IDO75787
DescriptionRenin receptor;Alternative Name- Renin/prorenin receptor;Alternative Name- ATPase H(+)-transporting lysosomal accessory protein 2;Alternative Name- ATPase H(+)-transporting lysosomal-interacting prote
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationMembrane; Single-pass type I membrane protein (Potential)
Developmental StageNA
SimilarityNA
Post Translational ModificationPhosphorylated.
FunctionFunctions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I; it may also play a role in the renin-angiotensin system (RAS).
Length350
Molecular Weight39008
ReferenceNA
HormoneP00797; Q6FI38
PDB IDNA