| Primary information |
|---|
| ID | 31646 |
| Uniprot ID | P21731 |
| Description | Thromboxane A2 receptor;TXA2-R;Alternative Name- Prostanoid TP receptor |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Post Translational Modification | NA |
| Function | Receptor for thromboxane A2 (TXA2); a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. In the kidney; the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. |
| Length | 369 |
| Molecular Weight | 40092 |
| Reference | NA |
| Hormone | 1368 |
| PDB ID | 1LBN;
|