Detailed description page of Hmrbase2

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31644 details
Primary information
ID31644
Uniprot IDP35408
DescriptionProstaglandin E2 receptor EP4 subtype;PGE receptor; EP4 subtype;Alternative Name- Prostanoid EP4 receptor
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; Multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationNA
FunctionReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics; intestinal epithelial transport; adrenal aldosterone secretion; and uterine function.
Length488
Molecular Weight53119
ReferenceNA
Hormone1365; 1366
PDB IDNA