Detailed description page of Hmrbase2

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31641 details
Primary information
ID31641
Uniprot IDP34995
DescriptionProstaglandin E2 receptor EP1 subtype;Alternative Name- Prostanoid EP1 receptor;Alternative Name- PGE receptor; EP1 subtype
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; Multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationPhosphorylated (Potential).
FunctionReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.
Length402
Molecular Weight41801
ReferenceNA
Hormone1365; 1366
PDB IDNA