| Primary information |
|---|
| ID | 31639 |
| Uniprot ID | P43119 |
| Description | Prostacyclin receptor;Alternative Name- Prostanoid IP receptor;Alternative Name- PGI receptor;Alternative Name- Prostaglandin I2 receptor |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Post Translational Modification | Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling. Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. |
| Function | Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. |
| Length | 386 |
| Molecular Weight | 40956 |
| Reference | NA |
| Hormone | 1362; 1365 |
| PDB ID | NA
|