Primary information |
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ID | 31637 |
Uniprot ID | Q9NS75 |
Description | Cysteinyl leukotriene receptor 2;CysLTR2;Alternative Name- HG57;Alternative Name- HPN321;Alternative Name- hGPCR21 |
Organism | Homo sapiens |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular Location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | NA |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Post Translational Modification | NA |
Function | Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. Stimulation by BAY u9773; a partial agonist; induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 LTE4. |
Length | 346 |
Molecular Weight | 39635 |
Reference | NA |
Hormone | 1356; 1357; 1358 |
PDB ID | NA
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