Detailed description page of Hmrbase2

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31637 details
Primary information
ID31637
Uniprot IDQ9NS75
DescriptionCysteinyl leukotriene receptor 2;CysLTR2;Alternative Name- HG57;Alternative Name- HPN321;Alternative Name- hGPCR21
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; Multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationNA
FunctionReceptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. Stimulation by BAY u9773; a partial agonist; induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 LTE4.
Length346
Molecular Weight39635
ReferenceNA
Hormone1356; 1357; 1358
PDB IDNA