Primary information |
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ID | 31636 |
Uniprot ID | Q9NPC1 |
Description | Leukotriene B4 receptor 2;LTB4-R2;Alternative Name- Seven transmembrane receptor BLTR2;Alternative Name- Leukotriene B4 receptor BLT2;Alternative Name- LTB4 receptor JULF2 |
Organism | Homo sapiens |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular Location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | NA |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Post Translational Modification | NA |
Function | Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 12-epi-LTB4 LTB5 LTB3. |
Length | 389 |
Molecular Weight | 41525 |
Reference | NA |
Hormone | 1344; 1345; 1346; 1347; 1348; 1349; 1350; 1351; 13 |
PDB ID | NA
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