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31636 details
Primary information
ID31636
Uniprot IDQ9NPC1
DescriptionLeukotriene B4 receptor 2;LTB4-R2;Alternative Name- Seven transmembrane receptor BLTR2;Alternative Name- Leukotriene B4 receptor BLT2;Alternative Name- LTB4 receptor JULF2
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; Multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationNA
FunctionLow-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 12-epi-LTB4 LTB5 LTB3.
Length389
Molecular Weight41525
ReferenceNA
Hormone1344; 1345; 1346; 1347; 1348; 1349; 1350; 1351; 13
PDB IDNA