| Primary information |
|---|
| ID | 31634 |
| Uniprot ID | Q15722 |
| Description | Leukotriene B4 receptor 1;LTB4-R 1;Alternative Name- P2Y purinoceptor 7;P2Y7;Alternative Name- Chemoattractant receptor-like 1;Alternative Name- G-protein coupled receptor 16 |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Post Translational Modification | Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization. |
| Function | Receptor for extracellular ATP UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4; a potent chemoattractant involved in inflammation and immune response. |
| Length | 352 |
| Molecular Weight | 37557 |
| Reference | NA |
| Hormone | 1344; 1345; 1346; 1347; 1348; 1349; 1350; 1351; 13 |
| PDB ID | NA
|