| Primary information |
|---|
| ID | 31476 |
| Uniprot ID | P51128 |
| Description | Retinoic acid receptor RXR-alpha;Alternative Name- Retinoid X receptor alpha;Alternative Name- Nuclear receptor subfamily 2 group B member 1 |
| Organism | Xenopus laevis |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
| Subcellular Location | Nucleus |
| Developmental Stage | It is synthesized during oogenesis and persists during early cleavage; levels drop before gastrulation and remain low until the tailbud stage; and then increase in the later stages. |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | Sumoylated on Lys-134; which negatively regulates transcriptional activity. Desumoylated specifically by SENP6. |
| Function | Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). |
| Length | 488 |
| Molecular Weight | 53469 |
| Reference | NA |
| Hormone | NA |
| PDB ID | NA
|