Detailed description page of Hmrbase2

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31475 details
Primary information
ID31475
Uniprot IDQ05343
DescriptionRetinoic acid receptor RXR-alpha;Alternative Name- Retinoid X receptor alpha;Alternative Name- Nuclear receptor subfamily 2 group B member 1
OrganismRattus norvegicus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular LocationNucleus
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationSumoylated on Lys-113; which negatively regulates transcriptional activity. Desumoylated specifically by SENP6.
FunctionNuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer.
Length467
Molecular Weight51266
ReferenceNA
HormoneNA
PDB IDNA