| Primary information |
|---|
| ID | 31473 |
| Uniprot ID | P19793 |
| Description | Retinoic acid receptor RXR-alpha;Alternative Name- Retinoid X receptor alpha;Alternative Name- Nuclear receptor subfamily 2 group B member 1 |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Nucleus |
| Developmental Stage | NA |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | Sumoylated on Lys-108; which negatively regulates transcriptional activity. Desumoylated specifically by SENP6. |
| Function | Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. |
| Length | 462 |
| Molecular Weight | 50811 |
| Reference | NA |
| Hormone | NA |
| PDB ID | 1BY4; 1DSZ; 1FBY; 1FM6; 1FM9; 1G1U; 1G5Y; 1K74; 1L |