Detailed description page of Hmrbase2

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31469 details
Primary information
ID31469
Uniprot IDP51450
DescriptionNuclear receptor ROR-gamma;Alternative Name- Retinoid-related orphan receptor-gamma;Alternative Name- Nuclear receptor RZR-gamma;Alternative Name- Nuclear receptor subfamily 1 group F member 3;Alterna
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationNucleus (Probable)
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionOrphan nuclear receptor. Isoform 2 negatively regulates expression of TNFSF6/FASL and IL2 production in T-cells. It also binds to the TEA promoter and may participate in the regulation of DNA accessibility in the TCR-Jalpha locus.
Length516
Molecular Weight58117
ReferenceNA
HormoneNA
PDB IDNA