Detailed description page of Hmrbase2

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31466 details
Primary information
ID31466
Uniprot IDQ8R1B8
DescriptionNuclear receptor ROR-beta;Alternative Name- Retinoid-related orphan receptor-beta;Alternative Name- Nuclear receptor RZR-beta;Alternative Name- Nuclear receptor subfamily 1 group F member 2
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationNucleus (Probable)
Developmental StageHighest level in retina of stage E17.5 embryos. Lower level in postnatal and adult retina.
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionOrphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter.
Length470
Molecular Weight53118
ReferenceNA
HormoneNA
PDB IDNA