Detailed description page of Hmrbase2

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31463 details
Primary information
ID31463
Uniprot IDP35398
DescriptionNuclear receptor ROR-alpha;Alternative Name- Retinoid-related orphan receptor-alpha;Alternative Name- Nuclear receptor RZR-alpha;Alternative Name- Nuclear receptor subfamily 1 group F member 1
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationNucleus (Probable)
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionOrphan nuclear receptor. Binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'.
Length556
Molecular Weight63036
ReferenceNA
Hormone1182; 1369
PDB ID1N83; 1S0X;