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31451 details
Primary information
ID31451
Uniprot IDP51126
DescriptionRetinoic acid receptor alpha;RAR-alpha;Alternative Name- Nuclear receptor subfamily 1 group B member 1
OrganismXenopus laevis
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular LocationNucleus
Developmental StageIt is synthesized during oogenesis and persists in the cleaving embryo at approximately constant levels until it is degraded just before gastrulation.
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionThis is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.
Length458
Molecular Weight50574
ReferenceNA
HormoneNA
PDB IDNA