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31449 details
Primary information
ID31449
Uniprot IDP11416
DescriptionRetinoic acid receptor alpha;RAR-alpha;Alternative Name- Nuclear receptor subfamily 1 group B member 1
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationNucleus
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationPhosphorylated. Phosphorylation does not change during cell cycle. Phosphorylation on Ser-77 is crucial for transcriptional activity.
FunctionThis is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.
Length462
Molecular Weight50735
ReferenceNA
HormoneNA
PDB IDNA